APPROACHES TO COMPLEXITY REDUCTION IN A SYSTEMS BIOLOGY RESEARCH ENVIRONMENT ( SYCAMORE ) Irina Surovtsova

نویسندگان

  • Irina Surovtsova
  • Sven Sahle
  • Jürgen Pahle
  • Ursula Kummer
چکیده

Due to the complexity of biochemical reaction networks, socalled complexity reduction algorithms play a crucial role for making simulations efficient and for dissecting biochemical networks into meaningful subnetworks for analysis. Here, different approaches are presented, which we are developing in the context of a computational research environment for systems biology (SYCAMORE). These approaches are based on time-scale decomposition, sensitivity analysis, and hybrid simulation methods.

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تاریخ انتشار 2006